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Colorado Initiative for Molecular Biotechnology (CIMB; BioFrontiers forerunner) established by 3 founders from 3 departments: Leslie Leinwand (MCDB), Kristi Anseth (ChBE), and Natalie Ahn (BCHM).

Nobel Laureate and former Howard Hughes Medical Institute President Tom Cech (BCHM; HHMI Investigator) returns to CU to serve as our 1st Director.

Construction begins on the Jennie Smoly Caruthers Biotechnology Building (JSCBB) on East Campus, made possible with a foundational gift from Marv Caruthers (BCHM).

The CU Board of Regents approves the establishment of the BioFrontiers Institute.

The Jennie Smoly Caruthers Biotechnology Building opens and achieves LEED Platinum certification. It houses the BioFrontiers Institute, Department of Biochemistry, and Department of Chemical and Biological Engineering.

The Interdisciplinary Quantitative Biology (IQ Bio) PhD Certificate Program is created and welcomes its 1st cohort of 8 students.

The JSCBB E Wing opens, increasing square footage for research labs, core shared facilities, teaching space, and meetings to 400,000 SF. This addition was supported by a generous gift from the .

BioFrontiers Education Programs staff and faculty from 5 departments establish the undergraduate Computational Bio (CBIO) Minor to teach students from diverse disciplines to combine computational thinking and algorithms to study biological problems and systems.

National Academy of Sciences member and former RNA Society President Roy Parker (BCHM; HHMI Investigator) begins as the 2nd Director of BioFrontiers.

BioFrontiers becomes the nucleus of the CU pandemic response, with leadership on the Scientific Steering Committee and running the saliva monitoring test, developed by the Parker Lab, out of a dedicated lab space and team in JSCBB.

The IQ Bio PhD Program celebrates its 10th anniversary with an alumni reunion gala and scientific symposium.

The 20th anniversary of the founding of CIMB, the forerunner of BioFrontiers. Faculty size also reaches 20.